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NASA and its collaborators, striving to lay the groundwork for a possible human mission to Mars in the 2030s, know they will not achieve their ambition unless they find solutions for this and other risks to the health of their astronauts, which include weakened muscles, stiffened arteries and loss of bone density. Rady, vice president for business development at Abbott Medical Optics, joined a group of scientists, former astronauts, venture capitalists and private-sector counterparts who were asked to help promote the development of new space-friendly instruments to measure and ultimately mitigate the impact of space travel on the human eye. Because they will be used in the remote reaches of outer space, and eventually even on the surface of Mars, the tools must be compact, easy for non-experts to use and require minimal maintenance. Ultimately, this could be a business opportunity for Abbott but not right away, Rady says. 쏷he things we셱e involved in could have value for the program down the road, but probably right now are not what their immediate needs are, she says. Companies in Orange County and L.A. have been deeply involved in space exploration for decades. Boeing and McDonnell Douglas in Huntington Beach, North American Rockwell in Seal Beach, and TRW in San Juan Capistrano all played important roles in the moon landings. Work being done by SpaceX in Hawthorne and Boeing to develop rockets and capsules are initial steps in a possible mission to Mars. That could now extend to medical technology companies. Rady says the main goal of her group for now is to identify smaller startup companies with relevant technology that can be adapted within less than a year for use in space. She wants to get the word out in Orange County, 쐀ecause we셱e such a hotbed of medical technology for ophthalmology. The NSBRI is offering grants of $100,000 to small companies that can meet its need for a quick turnaround of devices that will allow astronauts to measure and monitor their vision while in space. The deadline for the one-page grant applications is Jan. 16. The grants are the backbone of a program NSBRI launched last month, dubbed 쏺ision for Mars Challenge. 쏧t is about finding new, state-of-the-art ways to look at the eyes in space, says Dorit Donoviel, the agency셲 deputy chief scientist. 쏽ou can셳 take one of those giant machines you have in an optometrist셲 office. Everything has to be really small, really fine, but it has to give you clinical-grade data. And because NASA hopes to test the instruments aboard the International Space Station in the not-too-distant future, 쐗e need this quickly, says Donoviel. 쏷hat셲 the good thing about small companies: they can usually work on a shoestring and be very efficient. Because the tools will be small, easy for non-experts to use and require few repairs, they are likely to be a lot less expensive than the current earthbound technology and thus highly marketable on Earth, Donoviel notes. That is the main value for the companies developing them. Several years ago, Abbott scientists consulted on the James Webb Space Telescope, scheduled to be launched in the next decade, and then took the precision methods used to measure and polish the lenses and created iDesign, a LASIK eye correction treatment. 쏻e look at these things not only for solving space issues, but we also want to make sure that we are helping these young companies become more solid, Donoviel says. 쏛 lot of investors will look at these things and say, 쁚es interesting, and there셲 a market, but there셲 risk involved. What we셱e trying to do is take away some of the risk, so that when we셱e done with them, an investor is more likely to invest. But of course the driving motivation is to overcome a major hurdle to an eventual mission to Mars, which could be a round-trip journey of 140 million miles and up to two years depending on how long astronauts remain on the surface of the red planet. There is some gravity on Mars about 38 percent of Earth셲 and scientists hope that might be a lot easier on the body than zero gravity, though they are not certain. In any event, astronauts would still spend seven months in space getting there and seven months on the way back. That셲 longer than any human space voyage so far. Doctors and scientists have already seen worrying signs of ocular degeneration among astronauts who have spent three to six months in space, or even less. That includes swelling of the optic nerve, which can cause blindness, a flattening of the eyeball, and folded choroids, which can damage the retina. Astronauts also tend to become far-sighted in space, 쏿nd if you셱e in a spacecraft with all the instrumentation you셶e got to monitor, this causes serious problems, says Abbott셲 Rady. While scientists believe elevated pressure from shifting fluids is the main culprit, they are not entirely sure. That is a big part of what needs to be studied. 쏻e don셳 really have our arms around it, says Chiao, the former astronaut. He thinks the high sodium content of astronauts prepared meals and the high carbon dioxide content of recirculated air could share some of the blame. The rigorous resistance exercises astronauts do to minimize the loss of muscle mass can also elevate pressure in the head, he notes. It is also not known whether the impact on human eyes eventually plateaus or just keeps getting worse the longer astronauts stay in space. 쏷hat becomes important if you셱e talking about sending people to Mars, Chiao says. Of equal importance is determining which astronauts are more vulnerable, since the effects seem to vary so widely. 쏧f certain people are going to be susceptible, you want to know beforehand, because maybe they셱e not the right guy to send to Mars, Chiao says. Vision for Mars is part of a broader NSBRI program, created in 2011, to promote investment in technologies to measure and treat the whole panoply of health complications that can arise from space travel. In order to resolve the health concerns with confidence, the government must actually commit to a Mars mission and budget for it, says Chris Carberry, executive director of ExploreMars Inc., a Massachusetts-based nonprofit dedicated to achieving such a mission within 20 years. Carberry, who runs a workshop that studies the cost of going to Mars, says support for it is growing, not only because of the rich inter-planetary research opportunity it would provide but also because it seems financially feasible. 쏧t won셳 take huge increases in the NASA budget, he says. Carberry, like everyone involved in space exploration, knows that finding ways to safeguard astronaut health is an absolute prerequisite to landing humans on Mars. 쏧f we셱e 20 years out and we actually commit, he says, 쐗e have time to figure it out. Contact the writer: 714-796-2440 or [url=http://www.michaelkorshandbagsonsale.us.com]http://www.michaelkorshandbagsonsale.us.com[/url] Patriotism has acquired a kind of gamy flavor these days, particularly in a place as diverse as San Jose.
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